AVL Partners With InSilicoTrials To Extend Simulation Offering For Healthcare Industry

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AVL and InSilicoTrials (IST) have entered into a strategic partnership to integrate AVL FIRE™ M into the InSilicoTrials AI and modeling and simulation platform. This collaboration expands InSilicoTrials' solution offering and represents a significant advancement in providing state-of-the-art multiphysics simulation tools to the healthcare industry, enhancing product development and operational efficiency.

FIRE M, an advanced computational fluid dynamics (CFD) tool by AVL, is renowned for its ability to simulate single- and multiphase flows, non-reacting and reacting flows, heat transfer, and solid-state temperatures in complex systems. Traditionally utilized in the automotive sector, FIRE M's capabilities are now poised to benefit a broader range of industries such as pharma and life sciences thanks to this collaboration.

InSilicoTrials effectively leverages XPS (eXtended Particle Simulations), a sophisticated DEM (Discrete Element Method) simulation software, to provide detailed predictions of fluid-granular processes in pharmaceutical manufacturing. XPS – developed by the Research Center Pharmaceutical Engineering (RCPE) enables precise control and prediction of unit operations with its advanced contact models and massively parallel algorithms optimized for GPUs. This capability ensures unmatched accuracy and the fastest execution times, supporting comprehensive process optimization and failure analysis.

The synergy between FIRE M and XPS opens up new possibilities for integrated solutions, combining the strengths of CFD and DEM technologies. This integration is particularly advantageous in scenarios like the simulation of industrial-scale Wurster coaters, where understanding the interaction between particle dynamics and fluid flow is crucial.

Roland Wanker, Vice President Advanced Simulation Technologies, AVL

I am excited about the perspectives offered by our strategic partnership with InSilicoTrials. This partnership is a unique opportunity for us to expand towards a highly attractive market segment, especially by the envisaged FIRE M/XPS co-simulation solution offering.

– Roland Wanker, Vice President Advanced Simulation Technologies, AVL List GmbH